@ Lynx
Brzytwa Ockhama to założenie, które możesz sobie stosować gdy kupujesz tańsze spodnie,
a nie gdy modelujesz DNA rośliny, która przez 10 lat będzie wypierała skutecznie inne rośliny aby po 11 latach paść ofiarą "większej ryby" w środowisku naturalnym. Bo nagle wpadnie wirus który wpada raz na 10 lat i ją wytępi, a Ty będziesz jadł suchą ziemię obiecując sobie, że kolejna roślina będzie wolna od tego błędu w projektowaniu.
Mon 810 jest szkodliwa i wiadomo to powszechnie, nadania na szczurach tego dowiodły i nikt nie odważył się ich w sposób bezpośredni podważyć, to jest fakt (nikt nie przeprowadził kontr-badań).
@ PaZi- jesteś po prostu osobą niedoinformowaną, co udowodnię poniżej:
http://www.nature.co...cr2011158a.htmlOur previous studies have demonstrated that stable microRNAs (miRNAs) in mammalian serum and plasma are actively secreted from tissues and cells and can serve as a novel class of biomarkers for diseases, and act as signaling molecules in intercellular communication. Here, we report the surprising finding that exogenous plant miRNAs are present in the sera and tissues of various animals and that these exogenous plant miRNAs are primarily acquired orally, through food intake. MIR168a is abundant in rice and is one of the most highly enriched exogenous plant miRNAs in the sera of Chinese subjects. Functional studies in vitro and in vivo demonstrated that MIR168a could bind to the human/mouse low-density lipoprotein receptor adapter protein 1 (LDLRAP1) mRNA, inhibit LDLRAP1 expression in liver, and consequently decrease LDL removal from mouse plasma. These findings demonstrate that exogenous plant miRNAs in food can regulate the expression of target genes in mammals.
co więcej:
Food-derived miRNAs may serve as a novel essential nutrient
It has been widely reported that downregulation of LDLRAP1 increases plasma LDL level35,36. In the present study, direct reduction of LDLRAP1 in mouse liver by RNAi significantly elevated plasma LDL level (Supplementary information, Figure S6A-S6C), confirming that LDLRAP1 is a gene candidate responsible for plasma LDL removal. Interestingly, an elevated level of MIR168a but a decreased LDLRAP1 in mouse liver were detected after just 6 h of rice feeding (Figures 2C and 5B), indicating that exogenous plant MIR168a from food intake can quickly change mouse liver LDLRAP1 level. Continuous downregulation of mouse liver LDLRAP1 level by MIR168a through rice feeding (Figure 6E and 6F) resulted in an elevation of the plasma LDL-cholesterol level after 3 days (Figure 6G), implicating a physiological relevance of food-derived plant MIR168a. Rice feeding-induced reduction of LDLRAP1 protein and elevation of plasma LDL-cholesterol level could be largely reversed by anti-MIR168a ASO (Figure 6I-6K), confirming that the rice feeding-mediated physiological alteration is specifically due to the targeting of mouse liver LDLRAP1 by MIR168a. This conclusion is also supported by the observation that chow diet with addition of mature MIR168a significantly enhanced the levels of mouse liver MIR168a (Figure 6N) and plasma LDL-cholesterol (Figure 6Q) but decreased mouse liver LDLRAP1 protein level (Figure 6O and 6P). Interestingly, food intake, possibly via intestinal epithelia of GI track, may represent a general pathway for uptake of food-derived or food-associated miRNAs. As shown in Supplementary information, Figure S7F-S7H, we added miR-150, an endogenous mammalian miRNA, into chow diet and fed mice with miR-150-enriched chow diet and normal chow diet, respectively. We found that miR-150 could also enter mouse liver and downregulate its target gene, c-Myb. Given that exogenous miRNAs in food or miRNAs that are 'added' into the food can enter the circulation and various organs of animals and play a role in regulating the physiological or pathophysiological conditions, food-derived exogenous miRNAs may be qualified as a novel nutrient component, like vitamins and minerals.
Zatem nukleotydy DNA i RNA nie ulegają degradacji absolutnej, miRNA sterują procesami zachodzącymi w komórkach swojego "biorcy" (jesteś tym, co jesz - zdaje się że to dość stare powiedzenie ..) a cała wiedza o GMO właśnie wzięła w łeb.
Konieczne byłoby dalsze prowadzenie badań w tym kierunku - JAK działa miRNA z żywności GMO vs JAK działa wobec normalnego pożywienia (niemodyfikowanego).
Kropka, dalsza dyskusja jest zbyteczna, Panowie - nauka zawiodła Was w kozi róg, dając niepodważalne dowody na to, że miRNA - zniekształcone przez mutację - na pewno odgrywa rolę w procesach komórkowych.
Previous studies have reported that the transfer of genetic material from one species to another may modulate the cellular functions of the recipient species50,51. Such examples include human miRNAs targeting viral genes50 and the translocation of host plant mRNAs into dodder (a parasitic plant)51.
However, to our knowledge, it was still unknown whether plant miRNAs could enter mammals and modulate mammalian cell functions.
By illustrating that plant miRNAs, such as MIR168a, can be delivered into animal serum and tissues through food intake and digestion and that exogenous MIR168a can target mammalian liver-specific LDLRAP1 in vitro and in vivo, the present study significantly extends our understanding of the role of miRNAs. With their robust stability and highly conserved sequences, secretory miRNAs can act not only in a cross-species, but also a cross-kingdom fashion.
In this sense, miRNAs may represent a novel class of universal modulators that play an important role in mediating animal-plant interactions at the molecular level. Like vitamins, minerals and other essential nutrients derived from food sources, plant miRNAs may serve as a novel functional component of food and make a critical contribution to maintaining and shaping animal body structure and function.
Extending from this concept, the intake of certain plant miRNAs generation after generation through a particular food source may leave an imprint on the genetic map of the human race. In conclusion, the discovery of plant miRNAs and their roles in the biology of mammalian cells and animal organs represents the first evidence of cross-kingdom transfer of functionally active miRNAs and opens a new avenue to explore miRNA-mediated animal-plant interactions.
Myślicie, że ustąpienie MOnsanto ze stanowiska w EU odbyło się tak po prostu?
Nie - wyszły na jaw fakty, które są niezbite i których nie sposób podważyć prostą "brzytwą okhama" - którą można zapodać ciemnemu chłopu na wsi - i który na to poleci.
Jeśli czegoś nie widać to nie znaczym, że tego nie ma - może po prostu nie ma światła
Lynx i PaZi - polecam Wam udanie się bez latarki i innych źródeł światła do jaskini - tam sobie przetestujecie Waszą brzytwę, w końcu jeśli czegoś nie widać to tego nie ma, prawda ?